Principal Research Scientist II, Biologics Drug Product Development

Company: AbbVie
Location: Irvine
Posted on: March 19, 2026

Job Description:

Company Description About AbbVie AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas including immunology, oncology and neuroscience - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com . Follow @abbvie on LinkedIn, Facebook , Instagram , X and YouTube. Job Description Seeking a highly motivated professional to join the highly potent compounds (HPC) drug product development team located at Irvine, CA. This individual will play a key role in advancing the companys early HPC pipeline with significant technical complexity. Reporting to the Center Director of Biologics Drug Product Development, the individual will be a key driver of scientific strategy around new biologics and innovative formulations with a special emphasis on HPC. The incumbent will take an important role in assuring BioDPDs compliance with SAT regulations. Responsibilities: Develops and achieves discipline strategy in alignment with functional goals and key scientific objectives. Advances scientific expertise within BioDPD. Proactively advises and shares knowledge and expert opinions with function, peers, and senior management. Mentors and trains functional colleagues and assess current and emerging business challenges enabling functional goal achievement. Collaborates with experts within the biologics and especially HPC discovery and development organizations to integrate scientific objectives into activities associated with development of new/improved products and technologies by advancing the fundamental understanding of HPC molecules and other biologics, especially with regard to drug product attributes. Translates late-stage drug product development requirements to early pipeline assessments, influencing the developability of new HPC molecules and formulation approaches as BioDPDs representative on early-stage programs in Discovery and Drug Delivery Science; performs due diligence evaluations for early-stage projects Acts as a scientific mentor across pipeline projects, with a special emphasis on sustained-release formulations and innovative tools to improve biologics characterization Builds a functional scientific strategy and drives its execution, influencing stakeholders to achieve external outreach. Ensures compliance with SAT standards and requirements as well as development of best practices as co-PI for Irvine-BioDPD Qualifications Bachelor's Degree in Science related field with 16 years of related industry experience; Master's Degree Science or PharmD with 14 years of related industry experience; PhD in Science or related field with 8 years of related industry experience. Proven ability to innovate with a history of new or improved product releases, including experience on early- and late-stage biological products from discovery support to BLA filings Interacts well with diverse groups within function and maintains strong working relationships with internal and external collaborators. Experienced in working with select agents, preferably as principal investigator Track record of scientific influencing and outreach Proven ability to elucidate structure-function relationships of biological molecules with specific emphasis on highly potent compounds Strong communication skills in interaction with management and the ability to condense complex scientific information into clear messages to drive scientific and pipeline projects Ability to influence in a cross-functional matrix Additional Information Applicable only to applicants applying to a position in any location with pay disclosure requirements under state orlocal law: The compensation range described below is the range of possible base pay compensation that the Companybelieves ingood faith it will pay for this role at the timeof this posting based on the job grade for this position.Individualcompensation paid within this range will depend on many factors including geographic location, andwemay ultimatelypay more or less than the posted range. This range may be modified in thefuture. We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick),medical/dental/visioninsurance and 401(k) to eligibleemployees. This job is eligible to participate in our short-term incentiveprograms. Note: No amount of payis considered to bewages or compensation until such amount is earned, vested, anddeterminable.The amount and availability of any bonus,commission, incentive, benefits, or any other form ofcompensation and benefitsthat are allocable to a particular employee remains in the Company's sole andabsolutediscretion unless and until paid andmay be modified at the Companys sole and absolute discretion, consistent withapplicable law. AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled. US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html

Keywords: AbbVie, Riverside , Principal Research Scientist II, Biologics Drug Product Development, Science, Research & Development , Irvine, California